Omega-3 fatty acids do not protect against CVD whereas palmitate is strongly detrimental The Alaska Inuit studies
Abstract
Omega-3 FAs do not prevent plaque formation and CVD. The overwhelming evidence from 3 Alaskan Inuit studies (involving 1635 participants) reveal that marine ω-3 fatty acids are not associated with either plaque or CVD. Even with an average consumption of 5 g of marine ω-3 FAs a day, the participants had more plaque than is reported for other US populations. On the other hand, excessive plasma concentration of palmitate, presumably related to palmitate and sugar consumption, is strongly detrimental to the cardiovascular system as a whole, as all CVD risk factors are associated with palmitate concentration in plasma. These conclusions confirm the results of the Swedish ULSAM 30 year prospective study, which linked high plasma concentrations of palmitate to cardiovascular mortality with no significant association between CVD mortality and plasma levels of ω-3 FAs.
The principal investigator (S.E.) has personally advised each participant about their individual screening results and their responsible health care providers about the results, conclusions of the studies and recommendations for prevention of CVD and diabetes.
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DOI: http://dx.doi.org/10.18103/imr.v3i5.452
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