Spinal anesthesia in clinical routine

Marie-Luise Ruebsam, Tilman Klein, Christian Hoenemann

Abstract


Spinal anesthesia (SPA) is a commonly technique used to block afferent (sensory) transmission. As a form of neuraxial blockade local anesthetics are injected in the subarachnoid space of the lumbar spine. SPA can be used in surgery of lower limb, anorectal surgery and provide an excellent and favorable alternative to general anesthesia in cesarean section. Onset and duration of action as well as adverse effects such as cardiotoxicity are directly related to pharmacological and –kinetic characteristics of local anesthetics. Hyperbaric solutions show faster time to achieve sensory blockade compared to isobaric. Opioids or other drugs like clonidine can be successfully used to prolong duration of blockade. Old drugs such as prilocaine open up new ways in ambulatory surgery.

When performing SPA, it is important to be aware of complication, their prevention and treatment. Systemic toxicity due to high intravascular concentration of LA is a rare, but life-threatening complication requiring immediate treatment. In contrast, hypotension due to sympathetic blockade and consecutive vasodilation is common and related to severe effects (e.g. reduction of uteroplacental perfusion leading to fetal acidosis and hypoxia). Fluid management and vasopressor therapy are controversially discussed in current literature.

Neurological complication such as spinal epidural hematoma or abscess often require neurosurgical therapy, while other such as transient neurological symptoms or post-dural puncture headache can be treated conservatively. 

It seems favorably to implement a hospital wide acknowledge standard how to perform SPA in different patient collectives. Continuous training and education for medical staff performing SPA on a regular basis in order to be able to deal confidently with adverse effects (e.g.) is highly recommended. 


Keywords


spinal anesthesia; local anesthetics; adverse effects; hypotension

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References


Abouleish, E., Vega, S., Blendinger, I., & Tio, T. O. (1975). Long-term follow-up of epidural blood patch. Anesthesia and analgesia, 54(4), 459–463.

Akin Takmaz, S., Unal Kantekin, C., Kaymak, C., & Basar, H. (2010). Treatment of post-dural puncture headache with bilateral greater occipital nerve block. Headache, 50(5), 869–872. doi:10.1111/j.1526-4610.2010.01656.x

Arnscheidt, C., & Mahlke, L. (2015). Advanced Trauma Life Support® (ATLS®): Auf Grundlage der 9. amerikanischen Auflage (1. dt. Aufl.). München: Elsevier, Urban & Fischer.

Arzola C, W. P. (2011). Efficacy of low-dose bupivacaine in spinal anaesthesia for Caesarean delivery: systematic review and meta-analysis. British journal of anaesthesia, 67(1), 36–42.

Axelsson, K., & Gupta, A. (2009). Local anaesthetic adjuvants: neuraxial versus peripheral nerve block. Current opinion in anaesthesiology, 22(5), 649–654. doi:10.1097/ACO.0b013e32832ee847

Bachmann, M., Pere, P., Kairaluoma, P., Rosenberg, P. H., & Kallio, H. (2012). Randomised comparison of hyperbaric articaine and hyperbaric low-dose bupivacaine along with fentanyl in spinal anaesthesia for day-case inguinal herniorrhaphy. European journal of anaesthesiology, 29(1), 22–27. doi:10.1097/EJA.0b013e32834a11be

Basurto Ona, X., Osorio, D., & Bonfill Cosp, X. (2015). Drug therapy for treating post-dural puncture headache. The Cochrane database of systematic reviews. (7), CD007887. doi:10.1002/14651858.CD007887.pub3

Bennasr, L., Ben Marzouk, S., Ajili, Z., Riahi, A., Jarraya, M. A., Massoudi, S.,. . . Maghrebi, H. (2014). Prevention de l'hypotension induite par la rachianesthesie au cours de la cesarienne programmee: Coremplissage par HEA 130/0,4 vs serum sale isotonique [Prevention of hypotension during spinal anesthesia for elective caesarean section: coloading with HAE 130/0.4 vs normal saline solution]. Annales francaises d'anesthesie et de reanimation, 33(12), 643–647. doi:10.1016/j.annfar.2014.10.004

Bern, S., Akpa, B. S., Kuo, I., & Weinberg, G. (2011). Lipid resuscitation: a life-saving antidote for local anesthetic toxicity. Current pharmaceutical biotechnology, 12(2), 313–319.

Bezov, D., Lipton, R. B., & Ashina, S. (2010). Post-dural puncture headache: part I diagnosis, epidemiology, etiology, and pathophysiology. Headache, 50(7), 1144–1152. doi:10.1111/j.1526-4610.2010.01699.x

Bier A. (1899). Versuche über die Cocainierung des Rückenmarks. Deutsche Zeitschrift für Chirurgie, 51, 361–368.

Bremerich, D. H., Fetsch, N., Zwissler, B. C., Meininger, D., Gogarten, W., & Byhahn, C. (2007). Comparison of intrathecal bupivacaine and levobupivacaine combined with opioids for Caesarean section. Current medical research and opinion, 23(12), 3047–3054. doi:10.1185/030079907X242764

Brodsky, J. B., & Lemmens, H. J. M. (2007). Regional anesthesia and obesity. Obesity surgery, 17(9), 1146–1149.

Brown, M. W., Yilmaz, T. S., & Kasper, E. M. (2016). Iatrogenic spinal hematoma as a complication of lumbar puncture: What is the risk and best management plan? Surgical neurology international, 7(Suppl 22), S581-9. doi:10.4103/2152-7806.189441

Burm, Anton G.L., van Kleef, Jack W. (1994). Pharmacokinetics of Local Anesthetics. In T. A. Bowdle, A. Horita, & E. D. Kharasch (Eds.), The Pharmacologic basis of anesthesiology. Basic science and practical applications (pp. 195–216). New York: Churchill Livingstone.

Bursch, N. (2008). spinal needles. Retrieved from https://upload.wikimedia.org/wikipedia/commons/f/fe/Spinal-needles.JPG

Butterworth, J. F., 4th., & Strichartz, G. R. (1990). Molecular mechanisms of local anesthesia: a review. Anesthesiology, 72(4), 711–734.

Caplan, R. A., Ward, R. J., Posner, K., & Cheney, F. W. (1988). Unexpected cardiac arrest during spinal anesthesia: a closed claims analysis of predisposing factors. Anesthesiology, 68(1), 5–11.

Carvalho, B., Collins, J., Drover, D. R., Atkinson Ralls, L., & Riley, E. T. (2011). ED(50) and ED(95) of intrathecal bupivacaine in morbidly obese patients undergoing cesarean delivery. Anesthesiology, 114(3), 529–535. doi:10.1097/ALN.0b013e318209a92d

Catterall, W., & Mackie, K. (1996). Local Anesthetics. In L. S. Goodman, A. Gilman, J. G. Hardman, A. G. Gilman, & L. E. Limbird (Eds.), Goodman & Gilman's the pharmacological basis of therapeutics (9th ed., p. 331). New York: McGraw-Hill, Health Professions Division.

Cave, G., & Harvey, M. (2009). Intravenous lipid emulsion as antidote beyond local anesthetic toxicity: a systematic review. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 16(9), 815–824. doi:10.1111/j.1553-2712.2009.00499.x

Chee, Y. L., Crawford, J. C., Watson, H. G., & Greaves, M. (2008). Guidelines on the assessment of bleeding risk prior to surgery or invasive procedures. British Committee for Standards in Haematology. British journal of haematology, 140(5), 496–504. doi:10.1111/j.1365-2141.2007.06968.x

Corning JL. (1885). Spinal anesthesia and local medication of the cord. New York Medical Journal, 42, 483–485.

Cossu, A. P., Giudici, L. M. de, Piras, D., Mura, P., Scanu, M., Cossu, M.,. . . Brazzi, L. (2015). A systematic review of the effects of adding neostigmine to local anesthetics for neuraxial administration in obstetric anesthesia and analgesia. International journal of obstetric anesthesia, 24(3), 237–246. doi:10.1016/j.ijoa.2015.05.002

Craß, D., Gerheuser, F., & Schwemmer, U. (2012). Regionalanästhesie. In R. Rossaint, C. Werner, & B. Zwißler (Eds.), Die Anästhesiologie (pp. 634–643). Berlin, Heidelberg: Springer Berlin Heidelberg.

Cyna, A. M., Andrew, M., Emmett, R. S., Middleton, P., & Simmons, S. W. (2006). Techniques for preventing hypotension during spinal anaesthesia for caesarean section. The Cochrane database of systematic reviews. (4), CD002251. doi:10.1002/14651858.CD002251.pub2

Dittmann, M., Schafer, H. G., Ulrich, J., & Bond-Taylor, W. (1988). Anatomical re-evaluation of lumbar dura mater with regard to postspinal headache. Effect of dural puncture. Anaesthesia, 43(8), 635–637.

Drasner, K. (2002). Local anesthetic neurotoxicity: clinical injury and strategies that may minimize risk. Regional anesthesia and pain medicine, 27(6), 576–580.

Erkuran, M. K., Duran, A., Kurt, B. B., & Ocak, T. (2015). Methemoglobinemia after local anesthesia with prilocaine: a case report. The American journal of emergency medicine, 33(4), 602.e1-2. doi:10.1016/j.ajem.2014.09.021

Errando, C. L., Peiro, C. M., Gimeno, A., & Soriano, J. L. (2014). Single shot spinal anesthesia with very low hyperbaric bupivacaine dose (3.75 mg) for hip fracture repair surgery in the elderly. A randomized, double blinded study. Revista espanola de anestesiologia y reanimacion, 61(9), 481–488. doi:10.1016/j.redar.2014.02.004

Etezadi, F., Karimi Yarandi, K., Ahangary, A., Shokri, H., Imani, F., Safari, S., & Khajavi, M. R. (2013). The effect of needle type, duration of surgery and position of the patient on the risk of transient neurologic symptoms. Anesthesiology and pain medicine, 2(4), 154–158. doi:10.5812/aapm.6916

Faccenda, K. A., & Finucane, B. T. (2001). Complications of regional anaesthesia Incidence and prevention. Drug safety, 24(6), 413–442.

Fattahi, Z., Hadavi, S. M. R., & Sahmeddini, M. A. (2015). Effect of ondansetron on post-dural puncture headache (PDPH) in parturients undergoing cesarean section: a double-blind randomized placebo-controlled study. Journal of anesthesia, 29(5), 702–707. doi:10.1007/s00540-015-2000-5

Fettes, P. D. W., Hocking, G., Peterson, M. K., Luck, J. F., & Wildsmith, J. A. W. (2005). Comparison of plain and hyperbaric solutions of ropivacaine for spinal anaesthesia. British journal of anaesthesia, 94(1), 107–111. doi:10.1093/bja/aei008

Flaatten, H., Rodt, S., Rosland, J., & Vamnes, J. (1987). Postoperative headache in young patients after spinal anaesthesia. Anaesthesia, 42(2), 202–205.

Forster, J. G. (2014). Short-acting spinal anesthesia in the ambulatory setting. Current opinion in anaesthesiology, 27(6), 597–604. doi:10.1097/ACO.0000000000000126

Forster, J. G., & Rosenberg, P. H. (2011). Revival of old local anesthetics for spinal anesthesia in ambulatory surgery. Current opinion in anaesthesiology, 24(6), 633–637. doi:10.1097/ACO.0b013e32834aca1b

Fournet-Fayard, A., & Malinovsky, J.-M. (2013). Cephalees post-breches meningees et blood-patch: aspects theoriques et pratiques [Post-dural puncture headache and blood-patch: theoretical and practical approach]. Annales francaises d'anesthesie et de reanimation, 32(5), 325–338. doi:10.1016/j.annfar.2013.02.014

Gao, L., Zheng, G., Han, J., Wang, Y., & Zheng, J. (2015). Effects of prophylactic ondansetron on spinal anesthesia-induced hypotension: a meta-analysis. International journal of obstetric anesthesia, 24(4), 335–343. doi:10.1016/j.ijoa.2015.08.012

Gitelman, A., Hishmeh, S., Morelli, B. N., Joseph, S. A., JR, Casden, A., Kuflik, P.,. . . Stephen, M. (2008). Cauda equina syndrome: a comprehensive review. American journal of orthopedics (Belle Mead, N.J.), 37(11), 556–562.

Glosten B. (2000). Anesthesia for obstetrics. In Anesthesia (5th ed., pp. 2024–2068). New York [u.a.]: Churchill Livingstone.

Goyal, L. D., Kaur, H., & Singh, A. (2015). Cauda equina syndrome after repeated spinal attempts: A case report and review of the literature. Saudi journal of anaesthesia, 9(2), 214–216. doi:10.4103/1658-354X.152892

Greene, N. M. (1985). Distribution of local anesthetic solutions within the subarachnoid space. Anesthesia and analgesia, 64(7), 715–730.

Habib, A. S. (2012). A review of the impact of phenylephrine administration on maternal hemodynamics and maternal and neonatal outcomes in women undergoing cesarean delivery under spinal anesthesia. Anesthesia and analgesia, 114(2), 377–390. doi:10.1213/ANE.0b013e3182373a3e

Habib, A. S., & Gan, T. J. (2006). Use of neostigmine in the management of acute postoperative pain and labour pain: a review. CNS drugs, 20(10), 821–839.

Hampl, K. F., Schneider, M. C., & Drasner, K. (1999). Toxicity of spinal local anaesthetics. Current opinion in anaesthesiology, 12(5), 559–564.

Hare, G. M., & Ngan, J. C. (1998). Density determination of local anaesthetic opioid mixtures for spinal anaesthesia. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 45(4), 341–346. doi:10.1007/BF03012026

Hartwell, B. L., Aglio, L. S., Hauch, M. A., & Datta, S. (1991). Vertebral column length and spread of hyperbaric subarachnoid bupivacaine in the term parturient. Regional anesthesia, 16(1), 17–19.

Heng Sia, A. T., Tan, K. H., Sng, B. L., Lim, Y., Chan, E. S. Y., & Siddiqui, F. J. (2015). Hyperbaric versus plain bupivacaine for spinal anesthesia for cesarean delivery. Anesthesia and analgesia, 120(1), 132–140. doi:10.1213/ANE.0000000000000443

Higuchi, R., Fukami, T., Nakajima, M., & Yokoi, T. (2013). Prilocaine- and lidocaine-induced methemoglobinemia is caused by human carboxylesterase-, CYP2E1-, and CYP3A4-mediated metabolic activation. Drug metabolism and disposition: the biological fate of chemicals, 41(6), 1220–1230. doi:10.1124/dmd.113.051714

Hocking, G., & Wildsmith, J. A. W. (2004). Intrathecal drug spread. British journal of anaesthesia, 93(4), 568–578. doi:10.1093/bja/aeh204

Hogan, Q. H., Prost, R., Kulier, A., Taylor, M. L., Liu, S., & Mark, L. (1996). Magnetic resonance imaging of cerebrospinal fluid volume and the influence of body habitus and abdominal pressure. Anesthesiology, 84(6), 1341–1349.

Honca, M., Dereli, N., Kose, E. A., Honca, T., Kutuk, S., Unal, S. S., & Horasanli, E. (2015). Low-dose levobupivacaine plus fentanyl combination for spinal anesthesia in anorectal surgery. Brazilian journal of anesthesiology (Elsevier), 65(6), 461–465. doi:10.1016/j.bjane.2014.01.007

Horlocker, T. T., & Wedel, D. J. (2000). Neurologic complications of spinal and epidural anesthesia. Regional anesthesia and pain medicine, 25(1), 83–98.

Jaradeh, S. (1993). Cauda equina syndrome: a neurologist's perspective. Regional anesthesia, 18(6 Suppl), 473–480.

Karaman, S., Kocabas, S., Uyar, M., Hayzaran, S., & Firat, V. (2006). The effects of sufentanil or morphine added to hyperbaric bupivacaine in spinal anaesthesia for caesarean section. European journal of anaesthesiology, 23(4), 285–291. doi:10.1017/S0265021505001869

Kararmaz, A., Kaya, S., Turhanoglu, S., & Ozyilmaz, M. A. (2003). Low-dose bupivacaine-fentanyl spinal anaesthesia for transurethral prostatectomy. Anaesthesia, 58(6), 526–530.

Katrin Waurick, Hanno Riess, Hugo Van Aken, Paul Kessler, Wiebke Gogarten, Thomas Volk. (2014). Rückenmarksnahe Regionalanästhesien und Thrombembolieprophylaxe/ antithrombotische Medikation: 3. überarbeitete Empfehlung der Deutschen Gesellschaft für Anästhesiologie und Intensivmedizin. Retrieved from Deutsche Gesellschaft für Anästhesiologie und Intensivmedizin e.V. (DGAI) website: http://www.awmf.org/uploads/tx_szleitlinien/001-005l_S1_R%C3%BCckenmarksnahe_Regionalan%C3%A4sthesie_Thromboembolieprophylaxe_2015-01.pdf

Klohr, S., Roth, R., Hofmann, T., Rossaint, R., & Heesen, M. (2010). Definitions of hypotension after spinal anaesthesia for caesarean section: literature search and application to parturients. Acta anaesthesiologica Scandinavica, 54(8), 909–921. doi:10.1111/j.1399-6576.2010.02239.x

Kuczkowski, K. M. (2004). Post-dural puncture headache in the obstetric patient: an old problem. New solutions. Minerva anestesiologica, 70(12), 823–830.

Kumar, N., Patidar, S. P., Joshi, D., & Kumar, N. (2010). Focal myelomalacia and syrinx formation after spinal anaesthesia. The Journal of the Association of Physicians of India, 58, 450–451.

Larsen, R. (2014). Anästhesie: Kapitel 22: Spinalanästhesie (10. Auflage). München: Elsevier Inc., Health Sciences Division.

Lavand'homme, P. M., Roelants, F., Waterloos, H., Collet, V., & Kock, M. F. de. (2008). An evaluation of the postoperative antihyperalgesic and analgesic effects of intrathecal clonidine administered during elective cesarean delivery. Anesthesia and analgesia, 107(3), 948–955. doi:10.1213/ane.0b013e31817f1595

Lavi, R., Rowe, J. M., & Avivi, I. (2010). Lumbar puncture: it is time to change the needle. European neurology, 64(2), 108–113. doi:10.1159/000316774

Laxenaire, M. C., Charpentier, C., & Feldman, L. (1994). Reactions anaphylactoides aux substituts colloidaux du plasma: incidence, facteurs de risque, mecanismes. Enquete prospective multicentrique francaise. Groupe Francais d'Etude de la Tolerance des Substituts Plasmatiques [Anaphylactoid reactions to colloid plasma substitutes: incidence, risk factors, mechanisms. A French multicenter prospective study]. Annales francaises d'anesthesie et de reanimation, 13(3), 301–310.

Liu, S., Carpenter, R. L., & Neal, J. M. (1995). Epidural anesthesia and analgesia. Their role in postoperative outcome. Anesthesiology, 82(6), 1474–1506.

Liu, S. S. (2000). Why are postdural puncture headaches still a problem? Regional anesthesia and pain medicine, 25(4), 347–349. doi:10.1053/rapm.2000.3028

Liu, S. S., Strodtbeck, W. M., Richman, J. M., & Wu, C. L. (2005). A comparison of regional versus general anesthesia for ambulatory anesthesia: a meta-analysis of randomized controlled trials. Anesthesia and analgesia, 101(6), 1634–1642. doi:10.1213/01.ANE.0000180829.70036.4F

Loubert, C. (2012). Fluid and vasopressor management for Cesarean delivery under spinal anesthesia: continuing professional development. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 59(6), 604–619. doi:10.1007/s12630-012-9705-9

Louis R. (1978). Topographic relationships of the vertebral column, spinal cord and nerve root. Anatomia clinica, 1(1), 3–12.

Lui, A. C., Polis, T. Z., & Cicutti, N. J. (1998). Densities of cerebrospinal fluid and spinal anaesthetic solutions in surgical patients at body temperature. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 45(4), 297–303. doi:10.1007/BF03012018

Mackenzie, A. R., Laing, R. B., Smith, C. C., Kaar, G. F., & Smith, F. W. (1998). Spinal epidural abscess: the importance of early diagnosis and treatment. Journal of neurology, neurosurgery, and psychiatry, 65(2), 209–212.

Makito, K., Kosugi, S., & Tsuzaki, K. (2011). Risk management in regional anesthesia: spinal epidural hematoma. Masui. The Japanese journal of anesthesiology, 60(11), 1250–1258.

Makris, A., Gkliatis, E., Diakomi, M., Karmaniolou, I., & Mela, A. (2014). Delayed spinal epidural hematoma following spinal anesthesia, far from needle puncture site. Spinal cord, 52 Suppl 1, S14-6. doi:10.1038/sc.2013.174

Martin, R. J., & Yuan, H. A. (1996). Neurosurgical care of spinal epidural, subdural, and intramedullary abscesses and arachnoiditis. The Orthopedic clinics of North America, 27(1), 125–136.

Marx, G. F. (1994). The first spinal anesthesia. Who deserves the laurels? Regional anesthesia, 19(6), 429–430.

Mather, L. E., Copeland, S. E., & Ladd, L. A. (2005). Acute toxicity of local anesthetics: underlying pharmacokinetic and pharmacodynamic concepts. Regional anesthesia and pain medicine, 30(6), 553–566. doi:10.1016/j.rapm.2005.07.186

McLeod, G. A. (2004). Density of spinal anaesthetic solutions of bupivacaine, levobupivacaine, and ropivacaine with and without dextrose. British journal of anaesthesia, 92(4), 547–551. doi:10.1093/bja/aeh094

Meininger, D., Byhahn, C., Kessler, P., Nordmeyer, J., Alparslan, Y., Hall, B. A., & Bremerich, D. H. (2003). Intrathecal fentanyl, sufentanil, or placebo combined with hyperbaric mepivacaine 2% for parturients undergoing elective cesarean delivery. Anesthesia and analgesia, 96(3), 852-8, table of contents.

Mercier, F. J. (2012). Cesarean delivery fluid management. Current opinion in anaesthesiology, 25(3), 286–291. doi:10.1097/ACO.0b013e3283530dab

Mulroy, M. F. (2002). Systemic toxicity and cardiotoxicity from local anesthetics: incidence and preventive measures. Regional anesthesia and pain medicine, 27(6), 556–561.

Mulroy, M. F. (2005). Local anesthetics: helpful science, but don't forget the basic clinical safety steps. Regional anesthesia and pain medicine, 30(6), 513–515. doi:10.1016/j.rapm.2005.08.010

Nag, D. S., Samaddar, D. P., Chatterjee, A., Kumar, H., & Dembla, A. (2015). Vasopressors in obstetric anesthesia: A current perspective. World journal of clinical cases, 3(1), 58–64. doi:10.12998/wjcc.v3.i1.58

Nair, G. S., Abrishami, A., Lermitte, J., & Chung, F. (2009). Systematic review of spinal anaesthesia using bupivacaine for ambulatory knee arthroscopy. British journal of anaesthesia, 102(3), 307–315. doi:10.1093/bja/aen389

Neal, J. M., Kopp, S. L., Pasternak, J. J., Lanier, W. L., & Rathmell, J. P. (2015). Anatomy and Pathophysiology of Spinal Cord Injury Associated With Regional Anesthesia and Pain Medicine: 2015 Update. Regional anesthesia and pain medicine, 40(5), 506–525. doi:10.1097/AAP.0000000000000297

Ngan Kee, W. D. (2010). Prevention of maternal hypotension after regional anaesthesia for caesarean section. Current opinion in anaesthesiology, 23(3), 304–309. doi:10.1097/ACO.0b013e328337ffc6

Ngan Kee, W. D., Khaw, K. S., Ng, F. F., Ng, K. K. L., So, R., & Lee, A. (2014). Synergistic interaction between fentanyl and bupivacaine given intrathecally for labor analgesia. Anesthesiology, 120(5), 1126–1136. doi:10.1097/ALN.0000000000000118

Ngan Kee, W. D., Khaw, K. S., Tan, P. E., Ng, F. F., & Karmakar, M. K. (2009). Placental transfer and fetal metabolic effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery. Anesthesiology, 111(3), 506–512. doi:10.1097/ALN.0b013e3181b160a3

Niraj, G., Kelkar, A., & Girotra, V. (2014). Greater occipital nerve block for postdural puncture headache (PDPH): a prospective audit of a modified guideline for the management of PDPH and review of the literature. Journal of clinical anesthesia, 26(7), 539–544. doi:10.1016/j.jclinane.2014.03.006

Oh, A.-Y., Hwang, J.-W., Song, I.-A., Kim, M.-H., Ryu, J.-H., Park, H.-P.,. . . Do, S.-H. (2014). Influence of the timing of administration of crystalloid on maternal hypotension during spinal anesthesia for cesarean delivery: preload versus coload. BMC anesthesiology, 14, 36. doi:10.1186/1471-2253-14-36

Olofsson, C., Nygards, E.-B., Bjersten, A.-B., & Hessling, A. (2004). Low-dose bupivacaine with sufentanil prevents hypotension after spinal anesthesia for hip repair in elderly patients. Acta anaesthesiologica Scandinavica, 48(10), 1240–1244. doi:10.1111/j.1399-6576.2004.00504.x

Orendacova, J., Cizkova, D., Kafka, J., Lukacova, N., Marsala, M., Sulla, I.,. . . Katsube, N. (2001). Cauda equina syndrome. Progress in neurobiology, 64(6), 613–637.

Owczuk, R., Sawicka, W., Wujtewicz, M. A., Kawecka, A., Lasek, J., & Wujtewicz, M. (2005). Influence of spinal anesthesia on corrected QT interval. Regional anesthesia and pain medicine, 30(6), 548–552. doi:10.1016/j.rapm.2005.06.005

Pace, N. L. (2011). Intrathecal dosing for cesarean delivery in obese and nonobese patients. Anesthesiology, 115(4), 899-900; author reply 900. doi:10.1097/ALN.0b013e31822c5f05

Patton, D. E., Lee, W., Miller, J., & Jones, M. (1991). Maternal, uteroplacental, and fetoplacental hemodynamic and Doppler velocimetric changes during epidural anesthesia in normal labor. Obstetrics and gynecology, 77(1), 17–19.

Pfanner, G., Koscielny, J., Pernerstorfer, T., Gutl, M., Perger, P., Fries, D.,. . . Kozek-Langenecker, S. A. (2007). Praoperative Blutungsanamnese. Empfehlungen der Arbeitsgruppe perioperative Gerinnung der Osterreichischen Gesellschaft fur Anasthesiologie, Reanimation und Intensivmedizin [Preoperative evaluation of the bleeding history. Recommendations of the working group on perioperative coagulation of the Austrian Society for Anaesthesia, Resuscitation and Intensive Care]. Der Anaesthesist, 56(6), 604–611. doi:10.1007/s00101-007-1182-0

PhilippN. (2007). Prinzip der Durchführung einer Spinalanästhesie. Retrieved from https://commons.wikimedia.org/wiki/File%3APrinzip_der_Spinalanästhesie.png

Practice Guidelines for Obstetric Anesthesia: An Updated Report by the American Society of Anesthesiologists Task Force on Obstetric Anesthesia and the Society for Obstetric Anesthesia and Perinatology. (2016). Anesthesiology, 124(2), 270–300. doi:10.1097/ALN.0000000000000935

Reina, M. A., Alvarez-Linera, J., Lopez, A., Benito-Leon, J., Andres, J. A. de, & Sola, R. G. (2002). Aportaciones de la resonancia magnetica en la cefalea pospuncion dural y en pacientes que cursan con hipotension de liquido cefalorraquideo [Magnetic resonance in dural post-puncture headache in patient with cerebrospinal fluid hypotension]. Revista espanola de anestesiologia y reanimacion, 49(2), 89–100.

Roberts, S. W., Leveno, K. J., Sidawi, J. E., Lucas, M. J., & Kelly, M. A. (1995). Fetal acidemia associated with regional anesthesia for elective cesarean delivery. Obstetrics and gynecology, 85(1), 79–83.

Robson, S. C., Boys, R. J., Rodeck, C., & Morgan, B. (1992). Maternal and fetal haemodynamic effects of spinal and extradural anaesthesia for elective caesarean section. British journal of anaesthesia, 68(1), 54–59.

Roelants, F. (2006). The use of neuraxial adjuvant drugs (neostigmine, clonidine) in obstetrics. Current opinion in anaesthesiology, 19(3), 233–237. doi:10.1097/01.aco.0000192812.56161.f8

Roofthooft, E. (2009). Anesthesia for the morbidly obese parturient. Current opinion in anaesthesiology, 22(3), 341–346. doi:10.1097/ACO.0b013e328329a5b8

Roofthooft, E., & van de Velde, M. (2008). Low-dose spinal anaesthesia for Caesarean section to prevent spinal-induced hypotension. Current opinion in anaesthesiology, 21(3), 259–262. doi:10.1097/ACO.0b013e3282ff5e41

Rothschild, L., Bern, S., Oswald, S., & Weinberg, G. (2010). Intravenous lipid emulsion in clinical toxicology. Scandinavian journal of trauma, resuscitation and emergency medicine, 18, 51. doi:10.1186/1757-7241-18-51

Russell, I. F. (1995). Levels of anaesthesia and intraoperative pain at caesarean section under regional block. International journal of obstetric anesthesia, 4(2), 71–77.

Schoenfeld, A. J., & Wahlquist, T. C. (2015). Mortality, complication risk, and total charges after the treatment of epidural abscess. The spine journal : official journal of the North American Spine Society, 15(2), 249–255. doi:10.1016/j.spinee.2014.09.003

Seljogi, D., Wolff, A. P., Scheffer, G. J., van Geffen, G. J., & Bruhn, J. (2016). Correlation of bupivacaine 0.5% dose and conversion from spinal anesthesia to general anesthesia in cesarean sections. Acta anaesthesiologica Belgica, 67(1), 36–42.

Shamriz, O., Cohen-Glickman, I., Reif, S., & Shteyer, E. (2014). Methemoglobinemia induced by lidocaine-prilocaine cream. The Israel Medical Association journal : IMAJ, 16(4), 250–254.

Sia, A. T., Tan, K. H., Sng, B. L., Lim, Y., Chan, E. S. Y., & Siddiqui, F. J. (2013). Use of hyperbaric versus isobaric bupivacaine for spinal anaesthesia for caesarean section. The Cochrane database of systematic reviews. (5), CD005143. doi:10.1002/14651858.CD005143.pub2

Sng, B. L., Siddiqui, F. J., Leong, W. L., Assam, P. N., Chan, E. S., Tan, K. H., & Sia, A. T. (2016). Hyperbaric versus isobaric bupivacaine for spinal anaesthesia for caesarean section. The Cochrane database of systematic reviews, 9, CD005143. doi:10.1002/14651858.CD005143.pub3

Soens, M. A., Birnbach, D. J., Ranasinghe, J. S., & van Zundert, A. (2008). Obstetric anesthesia for the obese and morbidly obese patient: an ounce of prevention is worth more than a pound of treatment. Acta anaesthesiologica Scandinavica, 52(1), 6–19. doi:10.1111/j.1399-6576.2007.01483.x

Sorenson, E. J. (2008). Neurological injuries associated with regional anesthesia. Regional anesthesia and pain medicine, 33(5), 442–448. doi:10.1016/j.rapm.2005.08.011

Spector, L. R., Madigan, L., Rhyne, A., Darden, B. 2., & Kim, D. (2008). Cauda equina syndrome. The Journal of the American Academy of Orthopaedic Surgeons, 16(8), 471–479.

Stendell, L., Fomsgaard, J. S., & Olsen, K. S. (2012). There is room for improvement in the prevention and treatment of headache after lumbar puncture. Danish medical journal, 59(7), A4483.

Strupp, M., Schueler, O., Straube, A., Stuckrad-Barre, S. von, & Brandt, T. (2001). "Atraumatic" Sprotte needle reduces the incidence of post-lumbar puncture headaches. Neurology, 57(12), 2310–2312.

Tamilselvan, P., Fernando, R., Bray, J., Sodhi, M., & Columb, M. (2009). The effects of crystalloid and colloid preload on cardiac output in the parturient undergoing planned cesarean delivery under spinal anesthesia: a randomized trial. Anesthesia and analgesia, 109(6), 1916–1921. doi:10.1213/ANE.0b013e3181bbfdf6

Truhlar, A., Deakin, C. D., Soar, J., Khalifa, G. E. A., Alfonzo, A., Bierens, Joost J L M,. . . Nolan, J. P. (2015). European Resuscitation Council Guidelines for Resuscitation 2015: Section 4. Cardiac arrest in special circumstances. Resuscitation, 95, 148–201. doi:10.1016/j.resuscitation.2015.07.017

Turnbull, D. K. (2003). Post-dural puncture headache: Pathogenesis, prevention and treatment. British journal of anaesthesia, 91(5), 718–729. doi:10.1093/bja/aeg231

Ueyama, H., He, Y. L., Tanigami, H., Mashimo, T., & Yoshiya, I. (1999). Effects of crystalloid and colloid preload on blood volume in the parturient undergoing spinal anesthesia for elective Cesarean section. Anesthesiology, 91(6), 1571–1576.

Uslu, S., & Comert, S. (2013). Transient neonatal methemoglobinemia caused by maternal pudendal anesthesia in delivery with prilocaine: report of two cases. Minerva pediatrica, 65(2), 213–217.

van Tuijl, I., van Klei, W. A., van der Werff, D B M, & Kalkman, C. J. (2006). The effect of addition of intrathecal clonidine to hyperbaric bupivacaine on postoperative pain and morphine requirements after Caesarean section: a randomized controlled trial. British journal of anaesthesia, 97(3), 365–370. doi:10.1093/bja/ael182

Varrassi, G., Celleno, D., Capogna, G., Costantino, P., Emanuelli, M., Sebastiani, M.,. . . Niv, D. (1992). Ventilatory effects of subarachnoid fentanyl in the elderly. Anaesthesia, 47(7), 558–562.

Veeser, M., Hofmann, T., Roth, R., Klohr, S., Rossaint, R., & Heesen, M. (2012). Vasopressors for the management of hypotension after spinal anesthesia for elective caesarean section. Systematic review and cumulative meta-analysis. Acta anaesthesiologica Scandinavica, 56(7), 810–816. doi:10.1111/j.1399-6576.2011.02646.x

Voigt, C. L., & Murphy, M. O. (2015). Occipital nerve blocks in the treatment of headaches: safety and efficacy. The Journal of emergency medicine, 48(1), 115–129. doi:10.1016/j.jemermed.2014.09.007

Westphal, M., James, M. F. M., Kozek-Langenecker, S., Stocker, R., Guidet, B., & van Aken, H. (2009). Hydroxyethyl starches: different products--different effects. Anesthesiology, 111(1), 187–202. doi:10.1097/ALN.0b013e3181a7ec82

Wulf, H., Hampl, K., & Steinfeldt, T. (2013). Speed spinal anesthesia revisited: new drugs and their clinical effects. Current opinion in anaesthesiology, 26(5), 613–620. doi:10.1097/ACO.0b013e3283606b71

Zaric, D., & Pace, N. L. (2009). Transient neurologic symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics. The Cochrane database of systematic reviews. (2), CD003006. doi:10.1002/14651858.CD003006.pub3

Zink, W., & Graf, B. M. (2003). Toxikologie der Lokalanasthetika. Pathomechanismen-Klinik-Therapie [Toxicology of local anesthetics. Clinical, therapeutic and pathological mechanisms]. Der Anaesthesist, 52(12), 1102–1123. doi:10.1007/s00101-003-0617-5

Zoremba, M., & Wulf, H. (2010). Spinalanasthesie--Ambulante Spinalanasthesie--Neue Trends einer alten Technik [Spinal anaesthesia in day case surgery--Old technique--new trends]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 45(3), 176–180. doi:10.1055/s-0030-1249400

Zorrilla-Vaca, A., Healy, R., & Zorrilla-Vaca, C. (2016). Finer gauge of cutting but not pencil-point needles correlate with lower incidence of post-dural puncture headache: a meta-regression analysis. Journal of anesthesia, 30(5), 855–863. doi:10.1007/s00540-016-2221-2




DOI: http://dx.doi.org/10.18103/imr.v3i1.310

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