Childhood and Adolescent Melanoma—Where Do We Stand Today?
Abstract
The purpose of this review is to update physicians on recent advances in the prevention, diagnosis, and treatment of pediatric melanoma. The incidence of melanoma is rapidly increasing, creating a serious public health concern. Recent advances in understanding the mutational landscape of pediatric melanoma has demonstrated that the majority of conventional melanoma seen in adolescents is caused by Ultraviolet (UV)-induced DNA damage. Fostering effective strategies among individuals, physicians, communities, schools, and policy makers to reduce UV exposure in children is pivotal to reducing their future risk of melanoma. Furthermore, a national multidisciplinary collaborative effort is needed to collect data, promote biological studies, and develop diagnostic and therapeutic recommendations for this rare disease.
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DOI: http://dx.doi.org/10.18103/imr.v2i9.182
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