Update on a 12-Channel, Laboratory, Neuroprosthetic Platform for SCI: Respiration, Urinary, and Muscle Disuse Atrophy Applications
Abstract
The NeuRx® Diaphragm Pacing System (Synapse Biomedical Inc, Oberlin, Ohio) is used by individuals with tetraplegic spinal cord injury and includes Permaloc® electrodes that are placed on the ventral side of the diaphragm to stimulate the phrenic nerve for respiration as a functional electrical stimulation (FES) intervention. A new 12-Channel, Laboratory, Neuroprosthetic Platform is being developed as a collaborative effort between Synapse Biomedical Inc and our neuroprosthetic Laboratory at Hines VA Hospital Research Service. Several types of electrodes are in development for the platform: surface electrodes, Mapping Electrodes, Modified Intramuscular Electrodes, Suture Electrodes, a Multi-Lead Cable with Connectors. Multiple FES applications are being proposed: adding extradiaphragmatic muscles to diaphragm pacing for improved respiration and cough, urinary control using direct bladder wall stimulation and neuromodulation of the pudendal nerve, and management of muscle atrophy to reduce the risk of pressure ulcers. Thus, this new platform is reviewed for FES approaches and applications, device development and current results; future work is proposed. Funding Source: This investigation was based upon work supported by the Office of Research and Development, the Rehabilitation Research and Development Service of the Department of Veterans Affairs (A0348).
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DOI: http://dx.doi.org/10.18103/imr.v2i8.147
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